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1

Treatment of infantile-onset spinal muscular atrophy with nusinersen: a phase 2, open-label, dose-escalation study

Finkel, Richard S, Chiriboga, Claudia A, Vajsar, Jiri, Day, John W, Montes, Jacqueline, De Vivo, Darryl C, Yamashita, Mason, Rigo, Frank, Hung, Gene, Schneider, Eugene, Norris, Daniel A, Xia, Shuting,

Journal:

Year:

2016

Language:

english

File:

PDF, 2.52 MB

english, 2016

2

Antisense oligonucleotides correct the familial dysautonomia splicing defect in IKBKAP transgenic mice

Sinha, Rahul, Kim, Young Jin, Nomakuchi, Tomoki, Sahashi, Kentaro, Hua, Yimin, Rigo, Frank, Bennett, C Frank, Krainer, Adrian R

Journal:

Nucleic Acids Research

Year:

2018

Language:

english

File:

PDF, 5.11 MB

english, 2018

3

Assessment of patient decision-making capacity in the context of voluntary euthanasia for psychic suffering caused by psychiatric disorders: a qualitative study of approaches among Belgian physicians

Schweitser, Frank, Stuy, Johan, Distelmans, Wim, Rigo, Adelheid

Journal:

Journal of Medical Ethics

Year:

2020

File:

PDF, 191 KB

2020

4

Antisense oligonucleotide–directed inhibition of nonsense-mediated mRNA decay

Nomakuchi, Tomoki T, Rigo, Frank, Aznarez, Isabel, Krainer, Adrian R

Journal:

Nature Biotechnology

Year:

2015

Language:

english

File:

PDF, 700 KB

english, 2015

5

Activation of Frataxin Protein Expression by Antisense Oligonucleotides Targeting the Mutant Expanded Repeat

Li, Liande, Shen, Xiulong, Liu, Zhongtian, Norrbom, Michaela, Prakash, Thazha P., O'Reilly, Daniel, Sharma, Vivek K., Damha, Masad J., Watts, Jonathan K., Rigo, Frank, Corey, David R.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2018

Language:

english

File:

PDF, 1.04 MB

english, 2018

6

Conservative treatment of anterior chronic exertional compartment syndrome in the military, with a mid-term follow-up

Zimmermann, Wes O, Hutchinson, Mark Robert, Van den Berg, Ruud, Hoencamp, Rigo, Backx, Frank J G, Bakker, Eric W P

Journal:

BMJ Open Sport & Exercise Medicine

Year:

2019

Language:

english

File:

PDF, 288 KB

english, 2019

7

Transreac: a model for the calculation of combined chemical reactions and transport processes and its extension to a probabilistic model

Ellen Rigo, Frank Schmidt-Döhl, Matias Krauß, Harald Budelmann

Journal:

Cement and Concrete Research

Year:

2005

Language:

english

File:

PDF, 693 KB

english, 2005

8

Combined corrections for attenuation, depthdependent blur, and motion in cardiac SPECT: A multicenter trial

Jonathan M. Links, Lewis C. Becker, Pierre Rigo, Raymond Taillefer, Lawrence Hanelin, Frank Anstett, Darrell Burckhardt, Lonnie Mixon

Journal:

Journal of Nuclear Cardiology

Year:

2000

Language:

english

File:

PDF, 266 KB

english, 2000

9

Oxytocin activates mitogen-activated protein kinase and up-regulates cyclooxygenase-2 and prostaglandin production in human myometrial cells

Miklós Molnár, János Rigó Jr., Roberto Romero, Frank Hertelendy

Journal:

American Journal of Obstetrics and Gynecology

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

10

The RNA Tether from the Poly(A) Signal to the Polymerase Mediates Coupling of Transcription to Cleavage and Polyadenylation

Frank Rigo, Amir Kazerouninia, Anita Nag, Harold G. Martinson

Journal:

Year:

2005

Language:

english

File:

PDF, 1.42 MB

english, 2005

11

Rescue of hearing and vestibular function by antisense oligonucleotides in a mouse model of human deafness

Lentz, Jennifer J, Jodelka, Francine M, Hinrich, Anthony J, McCaffrey, Kate E, Farris, Hamilton E, Spalitta, Matthew J, Bazan, Nicolas G, Duelli, Dominik M, Rigo, Frank, Hastings, Michelle L

Journal:

Nature Medicine

Year:

2013

Language:

english

File:

PDF, 3.26 MB

english, 2013

12

Seismicity in central-western Pyrenees (France): A consequence of the subsidence of dense exhumed bodies

Souriau, Annie, Rigo, Alexis, Sylvander, Matthieu, Benahmed, Sébastien, Grimaud, Frank

Journal:

Year:

2014

Language:

english

File:

PDF, 2.50 MB

english, 2014

13

Stereochemistry of Glutamate Receptor Agonist Efficacy: Engineering a Dual-Specificity AMPA/Kainate Receptor †

Madden, Dean R., Cheng, Qing, Thiran, Shalita, Rajan, Shanti, Rigo, Frank, Keinänen, Kari, Reinelt, Stefan, Zimmermann, Herbert, Jayaraman, Vasanthi

Journal:

Year:

2004

Language:

english

File:

PDF, 106 KB

english, 2004

14

Peripheral SMN restoration is essential for long-term rescue of a severe spinal muscular atrophy mouse model

Hua, Yimin, Sahashi, Kentaro, Rigo, Frank, Hung, Gene, Horev, Guy, Bennett, C. Frank, Krainer, Adrian R.

Journal:

Year:

2011

Language:

english

File:

PDF, 583 KB

english, 2011

15

Stereochemistry of Glutamate Receptor Agonist Efficacy: Engineering a Dual-Specificity AMPA/Kainate Receptor,

Madden, Dean R., Cheng, Qing, Thiran, Shalita, Rajan, Shanti, Rigo, Frank, Keinänen, Kari, Reinelt, Stefan, Zimmermann, Herbert, Jayaraman, Vasanthi

Journal:

Year:

2006

File:

PDF, 5 KB

2006

16

Pathological impact of SMN 2 mis-splicing in adult SMA mice

Sahashi, Kentaro, Ling, Karen K. Y., Hua, Yimin, Wilkinson, John Erby, Nomakuchi, Tomoki, Rigo, Frank, Hung, Gene, Xu, David, Jiang, Ya-Ping, Lin, Richard Z., Ko, Chien-Ping, Bennett, C. Frank, Kraine

Journal:

EMBO Molecular Medicine

Year:

2013

Language:

english

File:

PDF, 1.22 MB

english, 2013

17

Towards a therapy for Angelman syndrome by targeting a long non-coding RNA

Meng, Linyan, Ward, Amanda J., Chun, Seung, Bennett, C. Frank, Beaudet, Arthur L., Rigo, Frank

Journal:

Year:

2014

Language:

english

File:

PDF, 11.13 MB

english, 2014

18

Motor neuron cell-nonautonomous rescue of spinal muscular atrophy phenotypes in mild and severe transgenic mouse models

Hua, Yimin, Liu, Ying Hsiu, Sahashi, Kentaro, Rigo, Frank, Bennett, C. Frank, Krainer, Adrian R.

Journal:

Genes & Development

Year:

2015

Language:

english

File:

PDF, 1.65 MB

english, 2015

19

Synthetic oligonucleotides recruit ILF2/3 to RNA transcripts to modulate splicing

Rigo, Frank, Hua, Yimin, Chun, Seung J, Prakash, Thazha P, Krainer, Adrian R, Bennett, C Frank

Journal:

Nature Chemical Biology

Year:

2012

Language:

english

File:

PDF, 891 KB

english, 2012

20

Regulation of the ESC transcriptome by nuclear long noncoding RNAs

Bergmann, Jan H., Li, Jingjing, Eckersley-Maslin, Mélanie A., Rigo, Frank, Freier, Susan M., Spector, David L.

Journal:

Genome Research

Year:

2015

Language:

english

File:

PDF, 6.28 MB

english, 2015

21

Effects on Murine Behavior and Lifespan of Selectively Decreasing Expression of Mutant Huntingtin Allele by Supt4h Knockdown

Cheng, Hui-Min, Chern, Yijuang, Chen, I-Hui, Liu, Chia-Rung, Li, Sih-Huei, Chun, Seung J., Rigo, Frank, Bennett, C. Frank, Deng, Ning, Feng, Yanan, Lin, Chyuan-Sheng, Yan, Yu-Ting, Cohen, Stanley N.,

Journal:

Year:

2015

Language:

english

File:

PDF, 1.09 MB

english, 2015

22

Poly(A) Signal-Dependent Transcription Termination Occurs through a Conformational Change Mechanism that Does Not Require Cleavage at the Poly(A) Site

Zhang, Huimin, Rigo, Frank, Martinson, Harold G.

Journal:

Year:

2015

Language:

english

File:

PDF, 1.95 MB

english, 2015

23

Systemic, postsymptomatic antisense oligonucleotide rescues motor unit maturation delay in a new mouse model for type II/III spinal muscular atrophy

Bogdanik, Laurent P., Osborne, Melissa A., Davis, Crystal, Martin, Whitney P., Austin, Andrew, Rigo, Frank, Bennett, C. Frank, Lutz, Cathleen M.

Journal:

Proceedings of the National Academy of Sciences

Year:

2015

Language:

english

File:

PDF, 1.50 MB

english, 2015

24

Reversal of phenotypes in MECP2 duplication mice using genetic rescue or antisense oligonucleotides

Sztainberg, Yehezkel, Chen, Hong-mei, Swann, John W., Hao, Shuang, Tang, Bin, Wu, Zhenyu, Tang, Jianrong, Wan, Ying-Wooi, Liu, Zhandong, Rigo, Frank, Zoghbi, Huda Y.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.86 MB

english, 2015

25

DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang, Wendy, Thomas, Benjamin, Flynn, Ryan A., Gavzy, Samuel J., Wu, Lin, Kim, Sangwon V., Hall, Jason A., Miraldi, Emily R., Ng, Charles P., Rigo, Frank W., Meadows, Sarah, Montoya, Nina R., Herrera

Journal:

Year:

2015

Language:

english

File:

PDF, 7.25 MB

english, 2015

26

Corrigendum: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang, Wendy, Thomas, Benjamin, Flynn, Ryan A., Gavzy, Samuel J., Wu, Lin, Kim, Sangwon V., Hall, Jason A., Miraldi, Emily R., Ng, Charles P., Rigo, Frank, Meadows, Sarah, Montoya, Nina R., Herrera, N

Journal:

Year:

2016

File:

PDF, 34 KB

2016

27

Tau splicing in vivo: Application in mouse models of tauopathy confers functional and pathological changes

Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Kebodeaux, Carey S., Norrbom, Michaela, Chun, Seung, Dawson, Hana N., Rigo, Frank, Bennett, C. Frank, Miller, Timothy M.

Journal:

Alzheimer's & Dementia

Year:

2015

Language:

english

File:

PDF, 141 KB

english, 2015

28

Increased 4R-Tau Induces Pathological Changes in a Human-Tau Mouse Model

Schoch, Kathleen M., DeVos, Sarah L., Miller, Rebecca L., Chun, Seung J., Norrbom, Michaela, Wozniak, David F., Dawson, Hana N., Bennett, C. Frank, Rigo, Frank, Miller, Timothy M.

Journal:

Year:

2016

Language:

english

File:

PDF, 2.05 MB

english, 2016

29

Antisense oligonucleotides delivered to the amniotic cavity in utero modulate gene expression in the postnatal mouse

Depreux, Frederic F., Wang, Lingyan, Jiang, Han, Jodelka, Francine M., Rosencrans, Robert F., Rigo, Frank, Lentz, Jennifer J., Brigande, John V., Hastings, Michelle L.

Journal:

Nucleic Acids Research

Year:

2016

Language:

english

File:

PDF, 1.74 MB

english, 2016

30

Mammary Tumor-Associated RNAs Impact Tumor Cell Proliferation, Invasion, and Migration

Diermeier, Sarah D., Chang, Kung-Chi, Freier, Susan M., Song, Junyan, El Demerdash, Osama, Krasnitz, Alexander, Rigo, Frank, Bennett, C. Frank, Spector, David L.

Journal:

Year:

2016

Language:

english

File:

PDF, 3.60 MB

english, 2016

31

Phosphinines versus mesoionic carbenes: a comparison of structurally related ligands in Au( i )-catalysis

Rigo, Massimo, Hettmanczyk, Lara, Heutz, Frank J. L., Hohloch, Stephan, Lutz, Martin, Sarkar, Biprajit, Müller, Christian

Journal:

Dalton Transactions

Year:

2017

Language:

english

File:

PDF, 1.25 MB

english, 2017

32

The Antisense Transcript SMN-AS1 Regulates SMN Expression and Is a Novel Therapeutic Target for Spinal Muscular Atrophy

d’Ydewalle, Constantin, Ramos, Daniel M., Pyles, Noah J., Ng, Shi-Yan, Gorz, Mariusz, Pilato, Celeste M., Ling, Karen, Kong, Lingling, Ward, Amanda J., Rubin, Lee L., Rigo, Frank, Bennett, C. Frank, S

Journal:

Year:

2017

Language:

english

File:

PDF, 4.04 MB

english, 2017

33

Recognition of c9orf72 Mutant RNA by Single-Stranded Silencing RNAs

Hu, Jiaxin, Rigo, Frank, Prakash, Thazha P., Corey, David R.

Journal:

Nucleic Acid Therapeutics (Formerly Oligonucleotides)

Year:

2017

Language:

english

File:

PDF, 739 KB

english, 2017

34

SMN deficiency in severe models of spinal muscular atrophy causes widespread intron retention and DNA damage

Jangi, Mohini, Fleet, Christina, Cullen, Patrick, Gupta, Shipra V., Mekhoubad, Shila, Chiao, Eric, Allaire, Norm, Bennett, C. Frank, Rigo, Frank, Krainer, Adrian R., Hurt, Jessica A., Carulli, John P.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.55 MB

english, 2017

35

Antisense oligonucleotide therapy for spinocerebellar ataxia type 2

Scoles, Daniel R., Meera, Pratap, Schneider, Matthew D., Paul, Sharan, Dansithong, Warunee, Figueroa, Karla P., Hung, Gene, Rigo, Frank, Bennett, C. Frank, Otis, Thomas S., Pulst, Stefan M.

Journal:

Year:

2017

Language:

english

File:

PDF, 4.62 MB

english, 2017

36

Disrupted neuronal maturation in Angelman syndrome-derived induced pluripotent stem cells

Fink, James J., Robinson, Tiwanna M., Germain, Noelle D., Sirois, Carissa L., Bolduc, Kaitlyn A., Ward, Amanda J., Rigo, Frank, Chamberlain, Stormy J., Levine, Eric S.

Journal:

Nature Communications

Year:

2017

Language:

english

File:

PDF, 2.51 MB

english, 2017

37

Antisense Oligonucleotide-Mediated Removal of the Polyglutamine Repeat in Spinocerebellar Ataxia Type 3 Mice

Toonen, Lodewijk J.A., Rigo, Frank, van Attikum, Haico, van Roon-Mom, Willeke M.C.

Journal:

Molecular Therapy — Nucleic Acids

Year:

2017

Language:

english

File:

PDF, 1.61 MB

english, 2017

38

Tuberculosis of the Testicle

Thomas, Gilbert J., Stebbins, Theodore L., Rigos, Frank J.

Journal:

The Journal of Urology

Year:

1940

Language:

english

File:

PDF, 232 KB

english, 1940

39

Rescue of peripheral vestibular function in Usher syndrome mice using a splice-switching antisense oligonucleotide

Vijayakumar, Sarath, Depreux, Frederic F., Jodelka, Francine M., Lentz, Jennifer J., Rigo, Frank, Jones, Timothy A., Hastings, Michelle L.

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 475 KB

english, 2017

40

Downregulation of Survivin contributes to cell-cycle arrest during postnatal cardiac development in a severe spinal muscular atrophy mouse model

Sheng, Lei, Wan, Bo, Feng, Pengchao, Sun, Junjie, Rigo, Frank, Bennett, C Frank, Akerman, Martin, Krainer, Adrian R, Hua, Yimin

Journal:

Human Molecular Genetics

Year:

2017

Language:

english

File:

PDF, 1.51 MB

english, 2017

41

Murine knockin model for progranulin-deficient frontotemporal dementia with nonsense-mediated mRNA decay

Nguyen, Andrew D., Nguyen, Thi A., Zhang, Jiasheng, Devireddy, Swathi, Zhou, Ping, Karydas, Anna M., Xu, Xialian, Miller, Bruce L., Rigo, Frank, Ferguson, Shawn M., Huang, Eric J., Walther, Tobias C.,

Journal:

Proceedings of the National Academy of Sciences

Year:

2018

Language:

english

File:

PDF, 1.95 MB

english, 2018

42

Antisense-mediated reduction of EphA4 in the adult CNS does not improve the function of mice with amyotrophic lateral sclerosis

Ling, Karen K., Jackson, Michaela, Alkam, Duah, Liu, Dawei, Allaire, Norm, Sun, Chao, Kiaei, Mahmoud, McCampbell, Alexander, Rigo, Frank

Journal:

Neurobiology of Disease

Year:

2018

Language:

english

File:

PDF, 1.32 MB

english, 2018

43

Targeting amyloid-β precursor protein, APP , splicing with antisense oligonucleotides reduces toxic amyloid-β production

Chang, Jennifer L., Hinrich, Anthony J., Roman, Brandon, Norrbom, Michaela, Rigo, Frank, Marr, Robert A., Norstrom, Eric M., Hastings, Michelle L.

Journal:

Molecular Therapy

Year:

2018

Language:

english

File:

PDF, 3.63 MB

english, 2018

44

Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

Zhang, Ke, Daigle, J. Gavin, Cunningham, Kathleen M., Coyne, Alyssa N., Ruan, Kai, Grima, Jonathan C., Bowen, Kelly E., Wadhwa, Harsh, Yang, Peiguo, Rigo, Frank, Taylor, J. Paul, Gitler, Aaron D., Rot

Journal:

Year:

2018

Language:

english

File:

PDF, 22.73 MB

english, 2018

45

Rescue of Outer Hair Cells with Antisense Oligonucleotides in Usher Mice Is Dependent on Age of Treatment

Ponnath, Abhilash, Depreux, Frederic F., Jodelka, Francine M., Rigo, Frank, Farris, Hamilton E., Hastings, Michelle L., Lentz, Jennifer J.

Journal:

Journal of the Association for Research in Otolaryngology

Year:

2018

Language:

english

File:

PDF, 2.97 MB

english, 2018

46

Retraction Note: DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions

Huang, Wendy, Thomas, Benjamin, Flynn, Ryan A., Gavzy, Samuel J., Wu, Lin, Kim, Sangwon V., Hall, Jason A., Miraldi, Emily R., Ng, Charles P., Rigo, Frank, Meadows, Sarah, Montoya, Nina R., Herrera, N

Journal:

Year:

2018

Language:

english

File:

PDF, 384 KB

english, 2018

47

Overcoming imatinib resistance conferred by the BIM deletion polymorphism in chronic myeloid leukemia with splice-switching antisense oligonucleotides

Liu, Jun, Bhadra, Malini, Sinnakannu, Joanna Rajeswary, Yue, Wan Lin, Tan, Cheryl Weiqi, Rigo, Frank, Ong, S. Tiong, Roca, Xavier

Journal:

Year:

2017

Language:

english

File:

PDF, 9.90 MB

english, 2017

48

Activating frataxin expression by single-stranded siRNAs targeting the GAA repeat expansion

Shen, Xiulong, Kilikevicius, Audrius, O'Reilly, Daniel, Prakash, Thazha P., Damha, Masad J., Rigo, Frank, Corey, David R.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 3.06 MB

english, 2018

49

Evaluation of potential effects of Plastin 3 overexpression and low-dose SMN-antisense oligonucleotides on putative biomarkers in spinal muscular atrophy mice

Strathmann, Eike A., Peters, Miriam, Hosseinibarkooie, Seyyedmohsen, Rigo, Frank W., Bennett, C. Frank, Zaworski, Phillip G., Chen, Karen S., Nothnagel, Michael, Wirth, Brunhilde, Singh, Ravindra N.

Journal:

Year:

2018

Language:

english

File:

PDF, 3.19 MB

english, 2018

50

Evaluation of the Effect of 2’-O-Methyl, Fluoro Hexitol, Bicyclo and Morpholino Nucleic Acid Modifications on Potency of GalNAc Conjugated Antisense Oligonucleotides in Mice

Prakash, Thazha P., Yu, Jinghua, Kinberger, Garth A., Low, Audrey, Jackson, Michaela, Rigo, Frank, Swayze, Eric E., Seth, Punit P.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2018

Language:

english

File:

PDF, 850 KB

english, 2018